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Why I recommend Dante Labs

We received our tailored rare disease report this morning. It is exactly what we needed. The results look like they will be very helpful and are more comprehensive than we have had within our own healthcare system. 

We did have delays, but always received courteous responses from the team. They are providing a much-needed service, where many of us face gaps, and offering those services at a great price, so I guess there are bound to be busy periods! 

I had difficulty sorting out the raw data, which was where our rare disease answers were to be found, but the rare disease report which arrived today is completely user-friendly.

This was a test for my son. I have a rare disease diagnosis which is life-threatening and autosomal dominant, but has never been a 100% certain diagnosis. My son’s results reflect broader testing and have thrown up some possible alternatives, which could have big implications for myself, my son and wider family.

I am really impressed by this service.

Thank you.

Diagnosis with Whole Genome Sequencing

Motor Neurone Disease, Myoadenylate Deaminase Deficiency, Hereditary Hemochromatosis and Inflammatory Myopathy.

Thomas knew all too well of these inherited diseases as family members had developed and been diagnosed with these in the past. Still young, he developed several symptoms related to these diseases. 

Yet, doctors could not diagnose his precise disease.

In his own words, "There has been a lot wrong with me and doctors could never give me a precise answer."

Thomas found his answer in the Whole Genome Sequencing.

Thomas came to Dante to understand his genome and identify rare diseases. What he gained was the possibility of diagnosis and the capability of moving forward to tackle his genetic variations, he would otherwise be unaware of. Not all physicians knew or understood what could be done, however, the ones that did know, acted on the data we supplied Thomas with and they worked together in the hope of bettering Thomas' life.

As with Thomas' case, finding the answers in our genetic make-up might not equate to a favorable answer, but it does equate to a truthful answer that can be acted upon. 

‘[Thomas had] been looking for answers for years and years but unfortunately many of the Doctors and Consultants work in grey areas where no definite answers are available. However, now because of the genetic data from Dante Labs all the pieces of the puzzle are fitting together’.

(*) Thomas' name has been changed to protect his privacy

Severe leg pain decreased thanks to whole genome analysis

Dante Labs has been collaborating with the Facebook Group Periodic Paralysis Genetics Resources to offer Whole Genome Sequencing to its members at especially convenient price. 

The results have been useful for both diagnosis and treatment. Elsa's story shows how to act on genetic results to improve daily life even when suffering from a severe condition such as periodic paralysis.

Born and raised in Sweden, Elsa had been suffering from severe leg pain for several years. The traditional medical approach had been a series of trials and errors. Then Elsa ordered a Whole Genome Sequencing from Dante Labs. Compared to traditional target panels, the Whole Genome Sequencing analyzes the entire DNA, hence looking for variants in any gene and even in non-coding regions. 

Dante Labs identified a pathogenic variant in Elsa's DNA in the AMPD1 gene. 

Empowered with this information and collaborating with her physician, Elsa is finally able to take a precise treatment for her specific variant. 

Her severe leg pain is finally decreased "because I know what to do now." - in her own words.


(*) Elsa's name has been changed to protect her privacy.