Term of Service

  • Information about us 

  • The service is operated by Dante Labs. Inc., whose principal place of business is at 379 West Broadway, Suite 538, New York NY 10012, United States of America (“Dante Inc.”) and by Dante Labs S.r.l., whose principal place of business is at Strada Statale, 17, 67100, L'Aquila (AQ), Italy (“Dante S.r.l.” and, together with Dante Inc., ”Dante Labs”, “We”, “Us”). Dante S.r.l. is the company in charge of the performance of the analysis, while Dante Inc. is the company in charge of the sale of the Services (as described below) to you.


  • Use of the Website. Acceptance of Terms

    1. To purchase the Services, you shall access Dante Labs’ website at www.dantelabs.com (“Website”).

    1. The use of the Services is subject to the express acceptance of these Terms of Service ("TOS"), except for the Ancillary Services (as defined below) to which specific terms of service may apply. You shall accept these TOS each time you purchase the Services (as defined below).

  • Prerequisites

  • You may not purchase the Service if (1) you are not of legal age to form a binding contract with Dante Labs, or (2) you are not allowed to receiving the Services under the laws of the jurisdiction in which you are resident or from which you use the Services.

    In addition to the conditions above, if you provide your own genetic information, you must be at least eighteen (18) years old to agree to these TOS on behalf of yourself or those for whom you have legal authority to agree.



  • Description of the Services  

    1. By ordering from the Website, you may purchase Dante Labs services which include the following:

    1. Analysis of your genotype generated by Dante S.r.l. through the processing of your saliva sample provided for DNA extraction (“Genome Sequencing Test”). Dante S.r.l. will perform the Genome Sequencing Test within 8 (eight) weeks from the receipt of your saliva sample. 
    2. Diagnostic analysis service for COVID-19 (“Covid Test”). Dante S.r.l. carries out Covid Test by means of (i) serological diagnostic tests by blood analysis, for the detection of COVID-19 antibodies, and (ii) swab tests containing biological material to detect the presence of the virus in the collected biological material. Dante S.r.l. will perform the Covid Test within 24 hours from the receipt of your sample. 

    Please note that for both the Genome Sequencing Test and Covid Test, you may ask Dante Labs to send you specialized personnel in order to assist you in the collection of your sample at your own domicile. For such assistance, Dante Labs may request you to pay some supplementary amount other than the amount payed for the Services; the price may be disclosed at the moment of your request. 

    1. Ancillary analysis test in relation to the Genome Sequencing Test (“Ancillary Services”), as listed in Annex 1. When buying any of Dante Labs Ancillary Services, you will be requested to specify the kit for which you are requesting such service by providing the kit identification barcode (“KitID”). Dante S.r.l. will be able to perform the requested Ancillary Service only after you provide the KitID. Some of the Ancillary Services may be subject to specific TOS and, in this case, you shall accept them, otherwise they are subject to the present TOS (together with Genome Sequencing Service, Covid Test and Ancillary Test, the “Services”). 

    1. If you intend to purchase the Genome Sequencing Test or the Covid Test, you shall follow the process as described below:

    • Order a personal sample collection kit: by accessing the Website, you will be able only to purchase the Services and order a personal sample collection kit;

    • Register your sample collection kit on Genome Manager website: by accessing the Genome Manager website you - or who will use the Genome Sequencing or the Covid Tests - agree that, to benefit from Dante Labs Services, you must create a personal account (“Genome Manager Account”) and register your kit. Whether you have not registered your kit at the Genome Manager, Dante Labs will contact you upon receipt of your kit. If you do not perform such registration within 3 (three) days from Dante Labs’ communication, Dante Labs will not proceed with the analysis of your kit and will destroy it. Finally, if the analysis performed on your sample fails, Dante Labs will send you another free kit up to a maximum of three times to allow you to collect the sample again.

    You acknowledge and agree that the Services are provided pursuant to the current state of the art of genetic research and technology in use by Dante S.r.l. at the time of the purchase or viewing. As research progresses and scientific knowledge and technology evolves, Dante S.r.l. is constantly innovating in order to provide the best possible experience for its users. You acknowledge and agree that the form and nature of the Services which Dante S.r.l. provides may change from time to time without prior notice to you. As part of this continuing innovation, you acknowledge and agree that Dante Labs may also permanently or temporarily stop to offer some of its Services (or any features within the Services) to you or to users generally at Dante Labs’ sole discretion, without giving any prior notice. 



  • Order and purchase of the Services

  • Orders: you can order Dante Labs’ Services by following the process outlined in the Website. You acknowledge that by placing an order at the Website you will be under an obligation to pay for the Services.

    Please read and check carefully your order at each stage of the order process.  By submitting an order through Dante Labs’ Website, you are confirming that the payment details provided on your order are valid and correct. The contract between you and Dante Labs will only be effective when We receive your payment. Dante Labs will charge the amount due on your chosen payment method among those listed on the Website after We receive your order. 

    In the event that you change your contact details after the purchase of the Services, it will be your sole responsibility to inform Dante Labs of such changes, so that Dante Labs can contact you about your order if necessary. 

    The price of the Services will be specified on the Website and it may change from time to time, but changes will not affect any order Dante Labs have already accepted.


    Price: Delivery costs may not be included in the price of the Genome Sequencing Test and Covid Test and may be added to the total amount due. You will be able to see the delivery charges for the sample collection kit on the checkout page of your order.



  • Withdrawal and Termination 

  • Withdrawal: As a consumer, you have the right to withdraw from this agreement after the purchase of the Genome Sequencing Test and Covid Test. You can exercise such rights by notifying Dante Labs Inc. at contact@dantelabs.com, within 14 (fourteen) days from the receipt of the sample collection kit. Please note that you will not be able to withdraw from this agreement after Dante Labs has received the sample collection kit filed with your biological material, since Dante S.r.l. will start to perform a service with the same “customized” nature


    Likewise, with reference to the purchase of the Ancillary Services, according to Article 59, letter c) of the Italian Consumer Code, you may not withdraw from this agreement because of the nature of the analysis to be considered as a “customized” service and, thus, Dante Labs will start immediately to perform the required Services. 


    Termination: Dante Labs may at any time, terminate this agreement if: (1) you have acted in a manner which shows that you do not intend to, are unable to comply with, or you have breached any of the provisions of the TOS; (2) is required to do so by law (for example, unlawfulness of the provision of the Services provided to you); (3) the Services are no longer provided by Dante Labs in your country of residence or in which you use the Services; or (4) at its sole discretion, the Services are no longer commercially available. 


  • User Representations 

  • 7.1 By accessing Dante Labs Services, you agree to acknowledge and represent as follows:


    1. You represent that you are eighteen (18) years old or more if you are providing a sample or accessing your genetic or health information.  
    2. You confirm and declare that providing a sample to Dante S.r.l. is not subject to any restriction in the country in which you reside and that your sample and data may be transferred and/or processed outside the country in which you reside.
    3. You give permission to Dante S.r.l. to perform, with reference to the Genome Sequencing Test, genotyping services on the DNA extracted from your saliva sample and, with reference to the Covid Test, serological diagnostic tests by blood analysis or swab tests containing biological material. Dante S.r.l. will only disclose the results of the performed analysis to you or to anyone that legally represents you or that you have specifically authorized. 
    4. You understand and accept that any information you learn from the Services is not a medical and/or clinical advice. It is not designed to independently diagnose, prevent, or treat any condition or disease or to ascertain the state of your health. 

    You also understand that the results from the performance of the Genome Sequencing Test are only intended for informational and research purposes and that it should always be analyzed by a doctor or other health-care professional. Please be advised that Dante Labs strongly recommends that you seek the advice of your doctor, physician or other health-care provider if you need a professional advice.

    1. You will be the only responsible for all the possible consequences resulting from your sharing with others the access to your genetic or health information and/or your report containing your analysis results.
    2. Whether you shall give your explicit consent for the processing of your genetic or health data for research purposes, pursuant to Dante Labs’ Privacy Information, you understand and acknowledge that providing any sample containing your blood or your biological material or having your genetic or biological information processed or providing your medical records or any other information about your health condition will not give you any property and/or other rights in any research that may be developed by Dante Labs or its collaborating partners. You specifically understand that you will not receive compensation for any research that include or result from the processing of your health or genetic information or any other information you may provide to Dante Labs within the performance of the Services.

    7.2 You agree that in case of breach of any one of these representations Dante Labs has the right to refuse to provide any and all Services (or any portion thereof) and you shall indemnify and hold Dante Labs harmless against any liability, costs, or damages arising out of the breach of the representation.


  • Limitation of Liability 

  • Dante Labs, within the limits allowed by applicable laws, shall not be liable for breach-of-contract damages that could not reasonably have foreseen on entering into this agreement. That includes any direct, indirect, incidental, special, consequential or exemplary damages related - but not limited - to (a) losses that were not caused by Dante Labs’ breach of contract; (b) the use or the inability to use the Services; (c) any action you take based on the information/results you receive after purchasing and using the Services; (d) the use or access to your reports results that was not caused by Dante Labs or (e) statements or conduct of any third party on the Services.


  • Disclaimer of Warranties 

  • Dante Labs makes no warranty that the Services and/or the quality of any products, information, or other material purchased or obtained by you through the Services will meet your expectations. 

    Moreover, by accepting these TOS you also acknowledge that: (a) the use of Dante Labs’ resources is done at your own discretion and risk and that you will be solely responsible for any damage to your computer system or loss of data that results from the download and/or use of any material obtained through the use of Dante Labs Services and (b) no advice or information related to the Services, whether oral or written, obtained by you from Dante Labs shall create any warranty if not expressly stated in these TOS.

    Finally, you accept that Dante Labs Services do not qualify as medical and/or professional advice on your health condition and do not substitute the advice of qualified professionals.



  • Privacy Policy 

  • In order to purchase and use the Services you must first acknowledge and agree to the Privacy Policyhttps://www.dantelabs.com/pages/checkout-privacy-information


         

  • Jurisdiction and Applicable Law

  • Any disputes with Dante Labs arising out of or relating to the agreement shall be governed by Italian law regardless of your country of origin or where you access Dante Labs. 

    If you are a consumer and have your habitual residence in the European Union, you may benefit from the additional protection provided by the mandatory rules of your country of residence, which means that you may bring a claim to enforce your consumer protection rights in connection with these TOS in the country in which you live. 

    Still, if you reside in the EU, the European Commission provides for an online dispute resolution platform, which you can access here: https://ec.europa.eu/consumers/odr







    ANNEX 1

    ANCILLARY SERVICES



    Report

    Category

    Description

    Ataxia

    Nervous System

    The Ataxia Report is based on the Complete Genome Test. For this reason, it analyzes all Common and Rare Variants associated with Ataxia instead of a limited number of genes, as for old genetic panels. Ataxia describes a lack of muscle control or coordination of voluntary movements. Along with environmental factors, Genetics plays a key role in regulating Ataxia.

    Nutrigenomic

    General

    The Nutrigenomic Report provides nutrition and diet advice based on full genome sequencing, including information on Fats, Omega-3 and Omega-6, Vitamins, Food Habits, Taste and Allergies, and Body Weight. Genetics plays a key role in how our body reacts to food, such as how fats and vitamins benefit the body, hunger levels, craving snacks, sweet foods, caffeine, metabolism, obesity and more. Fat: which fats are good for you? Vitamins: B2, B6, B12, C, D, And Dietary Habits Sweet Tastes Obesity and Body Weight Click here to see an example of your report.

    Diabetes

    General

    The Diabetes Report is based on the Complete Genome Test. For this reason, it analyzes all common and rare variants associated with diabetes instead of a limited number of genes, as for old genetic panels. Diabetes is a disease that affects the body's ability to produce or use insulin. Along with environmental factors, Genetics plays a key role in regulating diabetes.

    Congenital Miastenic Syndrome

    Immune System

    The Mystenic Congenital Syndrome Report is based on the Complete Genome Test. For this reason, it analyzes all Common and Rare Variants associated with Congenital Mystenic Syndrome instead of a limited number of genes, as for the old genetic panels. Congenital Miastenic Syndrome is a group of conditions characterized by muscle weakness (myastenia) that worsens with physical exertion. Along with environmental factors, Genetics plays a key role in regulating Congenital Mystenic Syndrome. Click here to see an example of your report 29 genes analyzed 100% of the genomic regions covered Intragenic and intergenic regions analyzed All variants reported.

    Circadian Rhythm

    Endocrine System, Nervous System

    The Circadian Rhythm Report is based on the Complete Genome Test. For this reason, it analyzes all common and rare variants associated with the Circadian Rhythm instead of a limited number of genes, as for older generation reports. The Circadian Rhythm Report analyzes more than 250 conditions with specific information about the following diseases related to the circadian rhythm: Sleep-wake program disorder Delayed phase type Sleep little Epilepsy of the dominant endoly frontal sleep syndrome and other less common conditions Along with environmental factors, Genetics plays a key role in regulating circadian rhythm. More than 85 genes analyzed 100% of the genomic regions covered Intragenic and intergenic regions analyzed All variants reported.

    Haematological

    Hematopoietic system

    The Hematological Report is based on the Complete Genome Test. For this reason, it analyzes all Common and Rare variants related to blood tissue instead of a limited number of genes, as for older generation reports. The Hematological Report analyzes more than 1860 conditions with specific information on the following blood-related diseases: Autoimmunity Porphyria Sferocitosis Thrombocytopenia Disfibrinogenemia Beta Talassemia Immunodeficiency Deficiency of Clotting Factors Cyclic Neutropenia Hemoglobin variants and other less common conditions Along with environmental factors, Genetics plays a key role in regulating blood More than 300 genes analyzed 100% of the genomic regions covered Intragenic and Intergenic Regions analyzed All variants reported.

    Graves disease

    Endocrine system

    The Graves Disease Report is based on the Complete Genome Test. For this reason, it analyzes all common and rare variants associated with Graves disease instead of a limited number of genes, as for old genetic panels. Graves Disease is a disorder of the immune system that results in the overproduction of thyroid hormones (hyperthyroidism). Along with environmental factors, Genetics plays a key role in regulating Graves disease.

    Gastroenterologic

    Gastrointestinal System

    The Gastroenterological Report is based on the Complete Genome Test. For this reason, it analyzes all Common and Rare Variants related to gastrointestinal diseases instead of a limited number of genes, as for older generation reports. The Gastroenterological Report analyzes more than 680 conditions with specific information on the following diseases related to the gastrointestinal tract: Crohn's disease Ulcerous Colitis Disease Inflammatory bowel disease Congenital lactase deficiency Family Coletrigridemia Quadrifacyysee progressive Pancreatitis Hereditary deficiency Bureaucratic-isomaltarese and other less common conditions Along with environmental factors, Genetics plays a key role in regulating gastrointestinal diseases More than 151 genes analyzed 100% of the genomic regions covered Intragenic and intergenic regions analyzed All variants reported.

    Sensory

    Sensory System

    The Sensory Report is based on the Complete Genome Test. For this reason, it analyzes all common and rare variants associated with the senses, including hearing, smell, somatosensory, taste and vision disorders instead of a limited number of genes, as for old genetic panels. Along with environmental factors, Genetics plays a key role in the regulation of the senses. More than 250 genes analyzed 100% of the genomic regions covered Intragenic and intergenic regions analyzed All variants reported.

    Pediatric

    Generic

    The Pediatric Report is based on the Complete Genome Test. For this reason, it analyzes all Common and Rare Variants related to pediatric diseases instead of a limited number of genes, as for older generation reports.

    The Paediatric Report analyzes more than 1480 conditions with specific information on the following paediatric diseases: Congenital Long QT Syndrome Cryptorchidism Rett's Syndrome Susceptibility of autism Benign familial neonatal convulsions Epilepsy Child Neuroaxonal Dystrophy and other less common conditions Together with environmental factors, Genetics plays a key role in the regulation of paediatric diseases More than 300 genes analyzed 100% of genomic regions covered Intragenic and intergenic regions analyzed All variants reported.

    Hereditary Cancer

    Generic

    The Hereditary Cancer Report is based on the Complete Genome Test. For this reason, it analyzes all Common and Rare Variants related to Cancer instead of a limited number of genes, as for older generation reports. The Hereditary Cancer Report analyzes more than 2130 conditions with specific information on the following diseases related to hereditary cancer: Anemia of Fanconi Myeloma Multiple Syndrome Cowden Adenocarcinoma Lung Syndrome Polyponopoly Cancer/Adenocarcinoma of the Pancreatic Family Breast Cancer Syndrome of Lynch Hepatocellular Carcinoma Li-Fraumeni Syndrome and other less common conditions Along with environmental factors, More than 300 genes analyzed 100% of the genomic regions covered Intragenic and intergenic regions analyzed All variants reported.

    Myeloma

    Cardiovascular System, Immune System

    l Multiple Myeloma Report is based on the Complete Genome Test. For this reason, it analyzes all common and rare variants associated with Multiple Myeloma instead of a limited number of genes, as for old genetic panels. Multiple myeloma is a cancer that takes shape in a type of white blood cell called plasma cells. Plasma cells help fight infections by creating antibodies that recognize and attack germs. Along with environmental factors, Genetics plays a key role in regulating Multiple Myeloma. Click here to see an example of your report 8 genes analyzed 100% of the genomic regions covered Intragenic and intergenic regions analyzed All variants reported Gene List: BRAF,CCND1,FCRL4,FGFR3,IRF4,LIG4,MAF,PWWP3A.

    Report SLA

    Nervous System

    The SLA Report is based on the Full Genome Test. For this reason, it analyzes all common and rare variants associated with ALS, rather than a limited number of genes, as in old genetic panels. ALS, or amyotrophic lateral sclerosis, is a progressive neurodegenerative disorder that affects neurons in the brain and spinal cord. Along with environmental factors, Genetics plays a key role in regulating ALS.

    Metabolic

    Metabolic system

    The Metabolic Report is based on the Complete Genome Test. For this reason, it analyzes all Common and Rare Variants related to metabolic diseases instead of a limited number of genes, as for older generation reports. The Metabolic Report analyzes more than 1940 conditions with specific information on the following diseases related to metabolism: Oxidative Stress Mitochondrial Diseases Hyperbilirubinemia/Gilbert Fenilcheton syndrome Glycogen accumulation diseases Gaucher's disease Urine disease in maple syrup Congenital glycoslation disorders and other less common conditions Along with environmental factors, Genetics plays a key role in regulating metabolic diseases More than 490 genes analyzed 100% of the genomic regions covered Intragenic and intergenic regions analyzed All the variants reported.

    Marfan syndrome

    Skeletal Muscle System

    The Marfan Syndrome report is based on the Complete Genome Test. For this reason, it analyzes all common and rare variants associated with Marfan Syndrome instead of a limited number of genes, as for old genetic panels. Marfan Syndrome is a genetic disorder that affects connective tissue. Along with environmental factors, Genetics plays a key role in regulating Marfan Syndrome. Click here to see an example of your report 30 genes analyzed 100% of the genomic regions covered Intragenic and intergenic regions analyzed All variants reported Gene List: ABL1, ADAMTS10, ADAMTS17, ADAMTSL4, BGN, CBS, COL1A1, COL1A2, COL2A1,  COL3A1, COL5A1, COL5A2, COL11A1, COL11A2, EFEMP2, FBN1, FBN2, MAT2A,  MED12, PLOD1, SKI, SLC2A10, SMAD3, SMAD6, TGFB2, TGFB3, TGFBR1,  TGFBR2, UPF3B, VCAN.

    Emiplegic Migraine

    Nervous System

    The Emiplegic Migraine Report is based on the Complete Genome Test. For this reason, it analyzes all common and rare variants associated with Emiplegic Migraine instead of a limited number of genes, as for old genetic panels. Emiplegic migraine is a rare type of migraine. Like other migraines, that hemiplegic one causes intense and pulsating pain, nausea and sensitivity to light and sound. It also causes temporary weakness, numbness and tingling, and paralysis on one side of the body. Along with environmental factors, Genetics plays a key role in regulating Emiplegic migraine.

    Epilepsy

    Nervous System

    The Epilepsy Report is based on the Complete Genome Test. For this reason, it analyzes all common and rare variants associated with Epilepsy instead of a limited number of genes, as for old genetic panels. Epilepsy is a disorder of the central (neurological) nervous system in which brain activity becomes abnormal, causing seizures or periods of unusual behavior, sensations and sometimes loss of consciousness. Along with environmental factors, Genetics plays a key role in regulating Epilepsy. Click here to see an example of your report 534 genes analyzed 100% of the genomic regions covered Intragenic and intergenic regions analyzed All variants reported.

    Parkinson - Alzeheimer 

    Nervous System

    The Parkinson's, Alzeheimer and Dementia Report is based on the Complete Genome Test. For this reason, it analyzes all common and rare variants associated with Parkinson's, Alzeheimer and Dementia instead of a limited number of genes, as for old genetic panels. Parkinson's, Alzeheimer and Dementia are progressive chronic neurological diseases. Along with environmental factors, Genetics plays a key role in regulating these diseases. Click here to see an example of your report 38 genes analyzed 100% of the genomic regions covered Intragenic and Intergenic Regions analyzed All variants reported.

    All Reports

    Packages

    List of reports included in the package: - ACMG - Fanconi Anemia - Rheumatoid Arthritis - Asthma - Ataxia - Autism - Autoimmunity - Legacy Cancer - Cardiovascular - Ulcerous Colitis - Dermatological - Dentist - Diabetes - Hemix - Emiplegic Migraine - Endocrinological - Epilepsy - Cystic Fibrosis - Gastroenterology - Crohn's disease - Graves Disease - Autoinflamatory Diseases - Mitochondrial Diseases - Methylation Mechanisms - Metabolic - Multiple Myeloma - Nephrological - Neurological - Osteopetrosis - Periodic Paralysis - Parkinson ' Alzeheimer - Dementia - Porphyria - Circadian Rhythm - Polycystic Ovary Syndrome - Syndrome WEST - Congenital Miastenic Syndrome - ALS - Oxidative Stress - Tachicardia Polymorphic Polymorphic Cateculaminergica (CPVT) - Connective Tissue - Von Willebrand.

    Report ACMG

    General

    This report analyzes all genes recommended by the American College of Medical Genetics and Genomics (ACMG) because they are considered valid in clinical practice. This means that there are clinical guidelines regarding conditions linked to variants included in these genes. ACMG recommends identifying these variants using advanced sequencing techniques, such as the comprehensive genome analysis offered by Dante Labs. The diseases analysed are the following: Familial adenomatous polyposis (FAP) Hereditary breast and ovarian cancer (HBOC) Li-Fraumenes syndrome (LFS) Peutz-Jeghers syndrome (PJS) Lynch syndrome - also known as hereditary non-polyposic colorectal cancer (HNPCC)-. MUTYH-associated polyposis (MAP) Von Hippel-Lindau syndrome (VHL) Multiple endocrine neoplasia type 1 (MEN1) Multiple endocrine neoplasia type 2 (MEN2) Familial marrow thyroid cancer Hamartoma syndrome Tumour PTEN Retinoblastoma Hereditary cancer - Pheochromocytoma syndrome (PGL/PCC) Tuberous sclerosis complex (TSC) Wilms tumour related to WT1 Neurofibromatosis type 2 (NF2) Juvenile polyposis syndrome (JPS) Marfan syndrome Loeys-Dietz syndrome (LDS) Aneurysms and/or thoracic aortic dissections (TAAD) Ehlers-Danlos syndrome, vascular type Hypertrophic vascular Cardiomyopathy Dilated ventricular tachycardia polymorphic catecholaminergic ventricular tachycardia (CPVT) Arrhythmogenic right ventricular cardiomyopathy (ARVC) Romano- Ward long QT syndrome Brugada syndrome (BrS) Familial hypercholesterolemia (FH) Wilson's disease Malignant hyperthermia susceptibility (MHS) Ornithine transcarbamylase deficiency (OTC).

    Dermatological

    Dermatology

    The Dermatological Report is based on the Complete Genome Test. For this reason, it analyzes all Common and Rare Skin Variants instead of a limited number of genes, as for older generation reports. The Dermatological Report analyzes more than 1100 conditions with specific information about the following skin-related diseases: Cheratodermia Palmoplantar Ittiosi vulgaris Pseudoxantoma elastic Skin Melanoma Hereditary Skin Melanoma Oculocutaneo Skin Exfoliation Syndrome Skin syxosay Skin Cancer Atopic Dermatitis Epidermolysis Bullosa Simple Xeroderma pigment and other conditions Genetics plays a key role in skin regulation Click here to see an example of your more than 209 genes analyzed 100% of genomic regions covered Intragenic and intergenic regions analyzed All variants reported.

    Crohn's disease

    Immune System

    The Crohn's Disease Report is based on the Complete Genome Test. For this reason, it analyzes all common and rare variants associated with Crohn's disease instead of a limited number of genes, as for old genetic panels. Crohn's disease is an inflammatory bowel disease. Causes inflammation of the digestive tract, which involves abdominal pain, severe diarrhea, fatigue, weight loss and malnutrition. Inflammation caused by Crohn's disease can affect different areas of the digestive tract depending on the person. Along with environmental factors, Genetics plays a key role in regulating Crohn's disease. Click here to see an example of your report 14 genes analyzed 100% of the genomic regions covered Intragenic and intergenic regions analyzed All variants reported Gene list: ATG16L1, HLA-DRB1, IL10, IL12B, IL23R, IRGM, JAK2, LRRK2, MUC2, NOD2, SLC22A4, SLC22A5, STAT3, TYK2.

    Osteopetrosis

    Skeletal Muscle System

    The Osteopetrosis Report is based on the Complete Genome Test. For this reason, it analyzes all common and rare variants associated with Osteopetrosis instead of a limited number of genes, as for old genetic panels. Osteopetrosis is a bone disease that makes bones too dense and easy to break (fracture) Along with environmental factors, Genetics plays a key role in regulating osteopetrosis. Click here to see an example of your report 14 genes analyzed 100% of the genomic regions covered Intragenic and intergenic regions analyzed All variants reported Gene list: AMER1, CA2, CLCN7 ,CTSK , FAM20C, FERMT3, LEMD3, LRP5, OSTM1, PLEKHM1, SNX10, TCIRG1, TNFRSF11A, TNFSF11.

    Polycystic Ovary Syndrome

    Polycystic Ovary Syndrome

    The Polycystic Ovary Syndrome report is based on the Complete Genome Test. For this reason, it analyzes all common and rare variants associated with Polycystic Ovary Syndrome instead of a limited number of genes, as for old genetic panels. Polycystic Ovary Syndrome is a condition that affects female hormones. Women who suffer from it produce higher amounts of male hormones. Along with environmental factors, Genetics plays a key role in regulating Polycystic Ovary Syndrome.

    Ulcerous Colitis

    Gastrointestinal System

    The Ulcerous Colitis Report is based on the Complete Genome Test. For this reason, it analyzes all common and rare variants associated with Ulcerous Colitis instead of a limited number of genes, as for old genetic panels. Ulcerous Colitis is an inflammatory bowel disorder that causes long inflammation and ulcers (plagues) in the digestive tract. Along with environmental factors, Genetics plays a key role in regulating Ulcerous Colitis. Click here to see an example of your report 6 genes analyzed 100% of the genomic regions covered Intragenic and intergenic regions analyzed All variants reported Gene List: ABCB1, IL10RA, IL10RB, IL23R, IRF5, PTPN2.

    Test Fitness

    b2bhealth

    Our Scientific Fitness Report has been developed in collaboration with professional and scientific sports coaches and provides advice for choosing the right type of exercise for you, optimizing your training and focusing your efforts. All based on science. Get advice on: How to choose the right exercises (38 conditions) How to improve your body (35 conditions) Injuries (19 conditions) Physical strength (3 conditions) Resistance Sprint Nutrigenomic in relation to sport (22 conditions) In addition, your DNA contains information about your body's reaction to exercise. Our Scientific Fitness Report provides you with information about Fitness, Resistance, Strength, Sprint and Injuries.

    Fanconi

    Anemia

    Cardiovascular System

    The Fanconi Anemia Report is based on the Complete Genome Test. For this reason, it analyzes all common and rare variants associated with Fanconi Anemia instead of a limited number of genes, as for old genetic panels. Fanconi Anemia is a rare recessive autosomal disease characterized by several phenotypic abnormalities, also present with rare heterosomal forms. The most relevant aspect of the condition is related to the function of the bone marrow, which fails to produce white blood cells, red blood cells or platelets. This deficit may mainly affect one or more of these elements. Along with environmental factors, Genetics plays a key role in regulating Fanconi Anemia.

    Autoimmune system

    Immune System

    The Autoimmune System Report is based on the Complete Genome Test. For this reason, it analyzes all common and rare variants associated with the autoimmune system instead of a limited number of genes, as for old genetic panels. The Autoimmune System Report analyzes more than an autoimmune disease is a condition in which your immune system mistakenly attacks your body. Along with environmental factors, Genetics plays a key role in regulating Asthma. Click here to see an example of your report 116 genes analyzed 100% of the genomic regions covered Intragenic and intergenic regions analyzed All variants reported.

    Ventricular Tachycardia Polymorphic Catecolaminergic

    Cardiovascular System

    The Polimorcular Polymorphic Polymorphic Tachycardia Report is based on the Complete Genome Test. For this reason, it analyzes all common and rare variants associated with Tachcardia Ventricular Polymorphic Polymorcular Catemorleminergica instead of a limited number of genes, as for the old genetic panels. The Tachicardia Ventricular Polymorphic Cateculaminergic is a condition characterized by an abnormal rhythm of the heart (arrhythmia). Along with environmental factors, Genetics plays a key role in regulating the Polymorphic Polymorphic Tachicardia Polymorcular. Click here to see an example of your report 9 genes analyzed 100% of the genomic regions covered Intragenic and intergenic regions analyzed All variants reported Gene List: ANK2,CALM1,CALM2,CALM3,CASQ2,KCNJ2,RYR2,TECRL,TRDN.

    Oxidative stress

    Metabolic system

    The Oxidative Stress Report is based on the Complete Genome Test. For this reason, it analyzes all common and rare variants associated with Oxidative Stress instead of a limited number of genes, as for old genetic panels. Oxidative stress is an imbalance between free radicals and the body's antioxidants. Along with environmental factors, Genetics plays a key role in regulating Oxidative Stress. Click here to see an example of your report 75 genes analyzed 100% of the genomic regions covered Intragenic and intergenic regions analyzed All variants reported.

    Ophthalmological

    Visual system

    The Ophthalmological Report is based on the Complete Genome Test. For this reason, it analyzes all Common and Rare Variants related to eye diseases instead of a limited number of genes, as for older generation reports. The Ophthalmological Report analyzes more than 1800 conditions with specific information about the following eye-related diseases: Macular degeneration Conephyte-red ectopia Lentis Bardet-Biedl Severe myopia Cataract Achromatopsia Retinopathy and other less common conditions Along with environmental factors, Genetics plays a key role in the regulation of eyes More than 400 genes analyzed 100% of the genomic regions covered Intragenic and intergenic regions analyzed All variants reported.

    Cardiovascular

    Cardiovascular System

    The Cardiovascular Report is based on the Complete Genome Test. For this reason, it analyzes all Common and Rare Variants linked to the heart instead of a limited number of genes, as for older generation reports. The Cardiovascular Report analyzes more than 6000 conditions with specific information about the following heart-related diseases: Tachicardia Ventricular Polymorphic PolymorphicCateculaminergica (CPVT) Ventricular arithmogenic cardiomyopathy right Brugada Aneurism Syndrome thoracic and aortic dissection LQ syndrome long Hypercholesterolemia family Pattern Wolff-Parkinson-White Congenital septtal congenital defect Family hypertrophic cardiomyopathy Fibrillation ventricular and other less common conditions Along with environmental factors , Genetics plays a key role in the regulation of the heart More than 300 genes analyzed 100% of the genomic regions covered Intragenic and intergenic regions analyzed All the variants reported.

    Pulmonary

    Respiratory System

    The Lung Report is based on the Complete Genome Test. For this reason, it analyzes all Common and Rare Lung Variants instead of a limited number of genes, as for older generation reports. The Pulmonary Report analyzes more than 590 conditions with specific information about the following lung-related diseases: Susceptibility of asthma Pulmonary Hypertension Cystic Fibrosis Disorders of the metabolism of tensioactive Chronic obstructive pulmonary disease Neonatal Respiratory Disorder Respiratory failure Lung occlusive disease and other less common conditions Along with environmental factors, Genetics plays a key role in regulating lung diseases More than 120 genes analysed 100% of the genomic regions covered Intragenic and intergenic regions analyzed All the variants reportedThe Lung Report is based on the Complete Genome Test. For this reason, it analyzes all Common and Rare Lung Variants instead of a limited number of genes, as for older generation reports. The Pulmonary Report analyzes more than 590 conditions with specific information on the following lung-related diseases: Susceptibility of asthma Pulmonary Hypertension Cystic Fibrosis Dysfunctions of the metabolism of tensioactive Chronic obstructive pulmonary disease Neonatal Respiratory disorder Respiratory failure Lung occlusive disease and other less common conditions Along with environmental factors, Genetics plays a key role in regulating lung diseases More than 120 genes analyzed 100% of the genomic regions covered Intragenic and intergenic regions analyzed All the variants reported.

    Connective tissue

    Generic

    The Connective Tissue Report is based on the Complete Genome Test. For this reason, it analyzes all Common and Rare Variants associated with Connective Tissue instead of a limited number of genes, as for older generation reports. The Connective Tissue Report analyzes more than 450 conditions with specific information about the following connective tissue-related diseases: Marfan Arthritis Rheumatoid Dystrophy Myoty Dystrophy Osteopetrosis Syndrome Ehlers-Danlos Syndrome Of Marshall Osteogenesis Imperfecta Loeys-Dietz Syndrome Multiple joint dislocations Along with environmental factors, Genetics plays a key role in regulating disorders. Click here to see an example of your report More than 200 genes analyzed 100% of the genomic regions covered Intragenic and intergenic regions analyzed All variants reported.

    Endocrine system

    Endocrine System

    The Endocrine System Report is based on the Complete Genome Test. For this reason, it analyzes all Common and Rare Variants related to diseases of the endocrine system instead of a limited number of genes, as for older generation reports. The Endocrine System Report analyzes more than 680 conditions with specific information on the following diseases related to the hormonal tract: Graves Disease Polycystic Ovary Syndrome Diabetes Comprehensive Androgen Resistance Syndrome Pseudoermaphrodism Hyperaldosteronism Hyperparathyroidism Deficiency of proopiomelanocortin Hypoomelatic Cushing Syndrome and other less common conditions Along with environmental factors, Genetics plays a key role in regulating hormones More than 228 genes analyzed 100% of the genomic regions covered Intragenic and Intergenic Regions analyzed All variants reported.

    Nefrologico

    Endocrine system

    The Nephrological Report is based on the Complete Genome Test. For this reason, it analyzes all Common and Rare variants related to kidney disease instead of a limited number of genes, as for older generation reports. The Nephrological Report analyzes more than 1240 conditions with specific information on the following kidney-related diseases: Polycystic Kidney Disease Pseudoipoaldosteronism Nephrolitiase Glomerulosclerosis Segmentary Focal Syndrome Alport Susceptibility to congenital kidney and urinary tract abnormalities Ipouric family kidneyemia Xanthinuria Primary Hyperossaluria and other less common conditions Along with environmental factors, Genetics plays a key role in regulating the kidneys More than 300 genes analyzed 100% of the genomic regions covered Intragenic and intergenic regions analyzed All variants reported.

    Neurological

    Nervous System

    The Neurological Report is based on the Complete Genome Test. For this reason, it analyzes all Common and Rare Variants related to neurological diseases instead of a limited number of genes, as for older generation reports. The Neurological Report analyzes more than 3600 conditions with specific information on the following kidney-related diseases: ALS Parkinson-Alzheimer-Dementia Athenaxia Epilepsy Congenital Syndrome Migraine Hemiplegic Periodic Paralysis of Charcot-Marie-Tooth spongy degeneration of the central nervous system Neuropathies Genetics plays a key role in regulating neurological diseases More than 800 genes analyzed 100% of the genomic regions covered Intragenic and intergenic regions analyzed All the variants reported.

    Rheumatoid arthritis

    Immune System

    The Rheumatoid Arthritis Report is based on the Complete Genome Test. For this reason, it analyzes all common and rare variants associated with Rheumatoid Arthritis instead of a limited number of genes, as for old genetic panels. Rheumatoid arthritis is a chronic inflammatory disorder that affects more than one joint. In some people, the condition can damage a wide variety of systems, including the skin, eyes, lungs, heart and blood vessels. Along with environmental factors, Genetics plays a key role in regulating Rheumatoid Arthritis. Click here to see an example of your report 16 genes analyzed 100% of the genomic regions covered Intragenic and intergenic regions analyzed All variants reported Gene List: ACP5,CD244,CD247,CIITA,GCH1, HLA-DRB1,IL10,IL2RA,IL6,MIF,NFKBIL1, PADI4,PTPN22,SLC22A4,STAT4.

    Periodic paralysis

    Skeletal Muscle System

    The Periodic Paralysis Report is based on the Complete Genome Test. For this reason, it analyzes all Common and Rare Variants associated with Periodic Paralysis instead of a limited number of genes, as for old genetic panels. Periodic paralysis is a rare genetic disorder. It causes sudden bouts of short-term muscle fatigue, hypertono, or paralysis. HypoPP is one of the conditions of periodic paralysis; dominant autosomic genetic diseases caused by mutations in sodium, potassium and calcium channel genes in skeletal muscle. In general, HypoPP is characterized by reversible bouts of muscle fatigue combined with decreasing concentrations of potassium in the blood. Along with environmental factors, Genetics plays a key role in regulating Periodic Paralysis. 98 genes analysed 100% of genomic regions covered Intragenic and intergenic regions analyzed All variants reported.

    Mitochondrial diseases

    Metabolic system

    The Mitochondrial Diseases Report is based on the Complete Genome Test. For this reason, it analyzes all common and rare variants associated with mitochondrial diseases instead of a limited number of genes, as for old genetic panels. Mitochondrial diseases are chronic (long-term), genetic and often hereditary diseases that occur when mitochondria fail to produce enough energy for the body to function properly. Along with environmental factors, Genetics plays a key role in regulating Mitochondrial Diseases.

    Porphyria

    Cardiovascular System

    The Porphyria Report is based on the Complete Genome Test. For this reason, it analyzes all common and rare variants associated with porphyria instead of a limited number of genes, as for old genetic panels. Porfiria is a set of problems caused by anomalies in the various chemical steps that lead to the production of the heme. Along with environmental factors, Genetics plays a key role in regulating Porphyria Click here to see an example of your report 9 genes analyzed 100% of the genomic regions covered Intragenic and intergenic regions analyzed All variants reported Gene List: ALAS2, CLPX, CPOX, FECH, HFE, HMBS, PPOX, UROD, UROS.

    Ehlers-Danlos syndrome

    Skeletal Muscle System

    The Ehlers-Danlos Syndrome report is based on the Complete Genome Test. For this reason, it analyzes all Common and Rare Variants associated with Ehlers-Danlos Syndrome instead of a limited number of genes, as for old genetic panels. Ehlers-Danlos Syndrome is a group of disorders that attack connective tissue that supports the skin, bones, blood vessels and many other organs and tissues. Problems in connective tissue cause signals and symptoms of these conditions, ranging from slightly loose joints to deadly complications. A correct diagnosis is crucial and must be validated as soon as possible. Along with environmental factors, Genetics plays a key role in regulating Ehlers-Danlos Syndrome. Click here to see an example of your report. 61 genes analyzed 100% of the genomic regions covered Intragenic and intergenic regions analyzed All the variants reported Click here to read the complete list of genes analyzed in this report.

    Charcot-Marie-Tooth disease

    Nervous System

    The Charcot-Marie-Tooth Disease Report is based on the Complete Genome Test. For this reason, it analyzes all Common and Rare Variants associated with Charcot-Marie-Tooth Disease instead of a limited number of genes, as for old genetic panels. Charcot-Marie-Tooth disease affects a group of disorders known as hereditary neuropathies of the senses and motor neuropathies that affect peripheral nerves. Damage to peripheral nerves that worsen over time can result in alteration or loss of sensitivity and decay (atrophy) of the muscles of the feet, legs, and hands. This disease has several implications, from insignificant variations of motor skills to pelvis atrophy, with a number of related effects such as difficulty walking and muscle pain. Along with environmental factors, Genetics plays a key role in regulating Charcot-Marie-Tooth disease. Click here to see an example of your report. 78 genes analysed 100% of genomic regions covered Intragenic and intergenic regions analyzed All variants reported.

    Cowden syndrome

    Dermatology

    The Cowden Syndrome report is based on the Complete Genome Test. For this reason, it analyzes all common and rare variants associated with Cowden Syndrome instead of a limited number of genes, as for old genetic panels. Cowden Syndrome is characterized by multiple non-tumor masses called amartoma and an increased risk of development of certain cancers. Often those who have this syndrome develop amartomas. Some are commonly found on the skin or mucous membranes (such as the wall of the mouth and nose), but can also be found in the intestines and other parts of the body. The growth of amartomas on the skin and mucous membranes is typically shown on people at the end of their twenties. Along with environmental factors, Genetics plays a key role in regulating Cowden Syndrome. 8 genes analyzed 100% of genomic regions covered Intragenic and intergenic regions analyzed All variants reported Gene list: AKT1,KLLN,PIK3CA,PTEN,SEC23B,SDHB,SDHC,SDHD.

    Methylation mechanisms

    General

    The Meditation Mechanisms Report is based on the Complete Genome Test. For this reason, it analyzes all Common and Rare Variants associated with The Meditation Mechanisms instead of a limited number of genes, as for the old genetic panels. Eukaryotic nuclear DNA is a well-organized entity grouped into nucleosomes, individual units of chromatin, then condensed into individual chromosomes. A chromosome is efficiently combined for systematic DNA replication, ensuring intact DNA propagation in the next generation of cells and organising different genes and regions of the genome for specific cellular functions. Replication occurs at many replication sources through the chromosome, approximately 100,000 pairs separated in DNA. Different signals between DNA packets can alert different machines to different cells to suppress or increase the expression of certain sections of DNA or specific genes. Along with environmental factors, Genetics plays a key role in regulating The Mechanisms of Meditation. Click here to see an example of your report. 39 genes analyzed 100% of genomic regions covered Intragenic and intergenic regions analyzed All variants reported.

    Leigh syndrome

    Nervous System

    The Leigh Syndrome report is based on the Complete Genome Test. For this reason, it analyzes all Common and Rare Variants associated with Leigh Syndrome instead of a limited number of genes, as for old genetic panels. Leigh Syndrome is a severe neurological disease that usually occurs in the first five years of life. This condition is characterized by a progressive loss of cognitive and motor skills (psychomotor regression) and typically leads to death between two and three years, usually due to respiratory arrest. Along with environmental factors, Genetics plays a key role in regulating Leigh Syndrome. 38 genes analyzed 100% of the genomic regions covered Intragenic and intergenic regions analyzed All variants reported Gene List: ADA,ADRB2,ALMS1,ALOX5,ARL6,BBS1,BBS4,CASP8,CCDC151,CCDC28B, CCL11,CDSN,CFTR,COMT,COX4I2,DDX41,DOCK8,ELOVL4,ERCC2,FLG, HLA-G,HNMT,IL13,MUC7,PLA2G7,SCGB3A2,TNF.

    West Syndrome

    Nervous System

    The West Syndrome report is based on the Complete Genome Test. For this reason, it analyzes all common and rare variants associated with West Syndrome instead of a limited number of genes, as for old genetic panels. West Syndrome is a constellation of symptoms characterized by epileptic/child spasms, abnormal brain waves patterns called ipsarrhythmia and intellectual disability. Along with environmental factors, Genetics plays a key role in regulating West Syndrome. Click here to see an example of your report 63 genes analyzed 100% of the genomic regions covered Intragenic and intergenic regions analyzed All variants reported Gene List: ARX,STK9,IFNG,TSC1,TSC2,PAH,QDPR,PIGW,CDKL5,CHD2,CNPY3,CPLX1,CUX2,CYFIP2,DENND5A,DMXL2,DNM1,DOCK7,EEF1A2,FGF12,FRR,PARS2S1L,GABBR2,GABRA1,GABRA5,GABRB3,GABRB1,GABRG2,GLS,GNAO1,GOT2,GRIN2B,GRIN2D,GUF1,HCN1,HNRNPU,ITPA,KCNA2,KCNB1,KCNQ2,KCNT1,KCNT2,MDH2,NECAP1,NEUROD2 ,NTRK2,PACS2,PCDH19,PHACTR1,PIGB,PIGP,PIGQ,PLCB1,PNKP,PPP3CA,RNF13,SCN1B,SCN2A,SCN3A,SCN8A,SIK1,YWHAG,UGP2.

    Dental

    General

    The Dental Report is based on the Complete Genome Test. For this reason, it analyzes all Common and Rare Variants associated with tooth diseases instead of a limited number of genes, as for old genetic panels. Dental pathology is any condition of the teeth that can be congenital or acquired. Sometimes congenital dental diseases are called dental abnormalities. These are among the most common diseases in humans. Dental pathology is usually separated from other types of dental problems, including enamel hypoplasia and tooth wear. Along with environmental factors, Genetics plays a key role in regulating dental pathologies. Click here to see an example of your report. 81 genes analysed 100% of genomic regions covered Intragenic and intergenic regions analyzed All variants reported.

    Cystic fibrosis

    Respiratory System

    The Cystic Fibrosis Report is based on the Complete Genome Test. For this reason, it analyzes all Common and Rare Variants associated with Cystic Fibrosis instead of a limited number of genes, as for old genetic panels. Cystic Fibrosis is a multisystem disease that affects the epithels of the airways, the exocrine pancreas, the intestine, the hepatobiliary system and the exocrine sweat glands. Morbidity includes progressive obstructive pulmonary disease with bronchiectasia, frequent admissions for lung disease, pancreatic failure and malnutrition, sinusitis and recurrent bronchitis and male infertility. Lung disease is the leading cause of morbidity and mortality in FC. Meconium ileus occurs at birth in 15%-20% of infants with FC. More than 95% of males with FC are infertile. Congenital absence of deferential vas (CAVD) is generally identified during the assessment of infertility or as an accidental feedback at the time of surgery. Hypoplasia or aplasia of deferential vessels and seminal vesicles can occur both bilaterally and unilaterally. Testicular development and function and spermatogenesis are usually normal. Along with environmental factors, Genetics plays a key role in regulating Cystic Fibrosis. Click here to see an example of your report. 10 genes analyzed 100% of genomic regions covered Intragenic and intergenic regions analyzed All variants reported.

    Autism

    Nervous System

    The Autism Report is based on the Complete Genome Test. For this reason, it analyzes all Common and Rare Variants associated with Autism instead of a limited number of genes, as for old genetic panels. Autistic Spectrum Disorder (ASD) is a condition that appears very early in childhood development, varies in severity, and is characterized by impaired social skills, communication problems and repetitive behaviors. These difficulties can interfere with the ability of affected individuals to function in social, academic and employment contexts. People with ASD also have an increased risk of psychiatric problems such as anxiety, depression, obsessive-compulsive disorder and eating disorders. Along with environmental factors, Genetics plays a key role in regulating Autism. Click here to see an example of your report. 35 genes analyzed 100% of the genomic regions covered Intragenic and intergenic regions analyzed All the variants reported Click here to read the complete list of genes analyzed in this report.

    Auto-inflammatory diseases

    Immune System

    The Autofimatory Diseases Report is based on the Complete Genome Test. For this reason, it analyzes all Common and Rare Variants associated with Autoinflamatory Diseases instead of a limited number of genes, as for old genetic panels. Autoinflamatory Diseases are a group of rare diseases caused by abnormal activation of the innate immune system, leading to recurrent episodes of fever and inflammation that can damage vital organs. Autoinflamatory diseases are different from autoimmune diseases such as rheumatoid arthritis and multiple sclerosis, which are caused by dysfunctions of the adaptive immune system. The most common symptom of auto-inflammatory diseases is recurrent fever. Other common symptoms are inflammation of muscles, joints, skin, gastrointestinal tract and internal organs. Along with environmental factors, Genetics plays a key role in regulating Ataxia. Click here to see an example of your report. 12 genes analysed 100% of genomic regions covered Intragenic and intergenic regions analyzed All variants reported.

    Von Willebrand

    Cardiovascular System

    The Von Willebrand Report is based on the Complete Genome Test. For this reason, it analyzes all Common and Rare Variants associated with Von Willebrand instead of a limited number of genes, as for old genetic panels. Von Willebrand is a hemorrhagic disorder that slows down the process of blood clotting, causing prolonged bleeding after an injury. People who suffer from this pathology often find themselves with easy bruising, loss of nosebleeds that last a long time and bleed or excessive oozing after injury, surgery or dental work. Mild forms of Von Willebrand's disease can only occur when abnormal bleeding occurs as a result of surgery or a serious injury. Symptoms of Von Willebrand's disease may change over time. Increased age, pregnancy, exercise and stress can cause less frequent bleeding symptoms. Along with environmental factors, Genetics plays a key role in regulating Von Willebrand. Click here to see an example of your report. 9 genes analyzed 100% of genomic regions covered Intragenic and intergenic regions analyzed All variants reported.