Autoinflammatory Panel

This product is only meant for customers who already purchased a Sequencing Test

Inflammation is a physiological phenomenon, a set of biological "events" implemented by our innate immune system to protect us from the attack of foreign particles such as bacteria and viruses, physical agents and chemical agents. However, when the inflammatory response explodes uncontrollably and without apparent cause, it can cause damage to the body.
Unlike autoimmune diseases, in which there is production of antibodies directed against endogenous targets, in autoinflammatory conditions it is the elements of natural immunity that are activated. Therefore, a picture of generalized inflammation is established which can manifest itself with the appearance of recurrent febrile episodes, skin rashes and joint pains.
The analysis takes into consideration the mutation of germline DNA, it investigates SNP and Indel mutations up to 150 bp.

• Available in less than 24 hours
• Based on Whole Genome Sequencing
• 15 genes are analyzed
• Investigates SNP and Indel mutations up to 150 bp

Conditions analyzed are:

• Familial Mediterranean Fever
• Periodic Fever

List of genes:

PSMB4
NLRP3
NLRC4
PSMB8
PSMB9
TNFAIP3
POMP
PSMA3
NOD2
PLCG2
NLRP12
STING1
MEFV
SAA1
TNFRSF1A