Skeletal and Connective Tissue Disorders Panel


Whole Genome Sequencing 30X

This product is only meant for customers who already purchased a Dante Genome Test

The genetic variants analyzed in this panel are closely related to or potentially the cause of sistemic mastocustosis conditions
Systemic mastocytosis is a rare disorder that affects the body's mast cells, leading to symptoms such as skin rash, abdominal pain, and anaphylaxis. Systemic mastocytosis is caused by mutations in genes involved in the regulation of mast cells, and this panel tests for genetic variants that are known to affect these processes.
This panel is designed for individuals with a family history of systemic mastocytosis or individuals with symptoms of the condition, such as skin rash, abdominal pain, and anaphylaxis. Genetic testing can confirm a diagnosis, provide information on disease severity and progression, and inform treatment and management decisions. Testing can also inform family planning decisions and provide reassurance for unaffected family members.

The analysis takes into consideration the mutation of germline DNA, it investigates SNP and Indel mutations up to 150 bp.

  • Available in less than 24 hours
  • Based on Whole Genome Sequencing
  • More than 5 genes analyzed
  • Investigates SNP and Indel mutations up to 150 bp

List of main conditions:
  • Myelodysplastic Syndrome
  • Systemic Mastocytosis With Associated Hematologic Neoplasm
  • Diffuse Cutaneous Mastocytosis

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